Between 1920 and 1921, Italian emigration to the United States dropped by 85% after the Emergency Quota Act, a severely restrictive immigration law, was passed by the US Congress. Using newly digitized data from Italian historical censuses in a difference-in-differences setting, we leverage variation in exposure across Italian districts to this large restriction on human mobility. More exposed districts display a sizable population increase. Moreover, the policy substantially hampered the adoption of labor-saving technology. Consistent with directed technology adoption theory, manufacturing employment increased markedly, and evidence suggests that "missing migrants," whose migration was inhibited by the Act, drive this result.